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Opiorphin is a master regulator of the hypoxic response in corporal smooth muscle cells

Men with sickle cell disease (SCD) risk developing priapism. Recognizing that SCD is a disease of hypoxia, we investigated the effect of hypoxia on gene expression in corporal smooth muscle (CSM) cells. Rat CSM cells in vitro were treated with CoCl(2) or low oxygen tension to mimic hypoxia. Hypoxic...

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Bibliografische gegevens
Hoofdauteurs: Fu, Shibo, Tar, Moses Tarndie, Melman, Arnold, Davies, Kelvin Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101653/
https://ncbi.nlm.nih.gov/pubmed/24803544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-248708
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