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Opiorphin is a master regulator of the hypoxic response in corporal smooth muscle cells

Men with sickle cell disease (SCD) risk developing priapism. Recognizing that SCD is a disease of hypoxia, we investigated the effect of hypoxia on gene expression in corporal smooth muscle (CSM) cells. Rat CSM cells in vitro were treated with CoCl(2) or low oxygen tension to mimic hypoxia. Hypoxic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fu, Shibo, Tar, Moses Tarndie, Melman, Arnold, Davies, Kelvin Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101653/
https://ncbi.nlm.nih.gov/pubmed/24803544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-248708
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