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Cell-generated traction forces and the resulting matrix deformation modulate microvascular alignment and growth during angiogenesis

The details of the mechanical factors that modulate angiogenesis remain poorly understood. Previous in vitro studies of angiogenesis using microvessel fragments cultured within collagen constructs demonstrated that neovessel alignment can be induced via mechanical constraint of the boundaries (i.e.,...

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Detalhes bibliográficos
Main Authors: Underwood, Clayton J., Edgar, Lowell T., Hoying, James B., Weiss, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101638/
https://ncbi.nlm.nih.gov/pubmed/24816262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00995.2013
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