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Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study

This study aims to understand the extent to which modulation of the Na(+)-K(+)-2Cl(−) cotransporter NKCC2 differential splicing affects NaCl delivery to the macula densa. NaCl absorption by the thick ascending limb and macula densa cells is mediated by apical NKCC2. A recent study has indicated that...

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Autors principals: Edwards, Aurélie, Castrop, Hayo, Laghmani, Kamel, Vallon, Volker, Layton, Anita T.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101627/
https://ncbi.nlm.nih.gov/pubmed/24848496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00158.2014
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