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Reliable Metabolic Flux Estimation in Escherichia coli Central Carbon Metabolism Using Intracellular Free Amino Acids

(13)C metabolic flux analysis (MFA) is a tool of metabolic engineering for investigation of in vivo flux distribution. A direct (13)C enrichment analysis of intracellular free amino acids (FAAs) is expected to reduce time for labeling experiments of the MFA. Measurable FAAs should, however, vary amo...

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Détails bibliographiques
Auteurs principaux: Okahashi, Nobuyuki, Kajihata, Shuichi, Furusawa, Chikara, Shimizu, Hiroshi
Format: Artigo
Langue:Inglês
Publié: MDPI 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4101513/
https://ncbi.nlm.nih.gov/pubmed/24957033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo4020408
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