Differential expression of miR200a-3p and miR21 in grade II–III and grade IV gliomas: Evidence that miR200a-3p is regulated by O(6)-methylguanine methyltransferase and promotes temozolomide responsiveness

Glioblastoma multiforme (GBM) is the most common primary brain tumor and is among the deadliest of human cancers. Dysregulation of microRNAs (miRNAs) expression is an important step in tumor progression as miRNAs can act as tumor suppressors or oncogenes and may affect cell sensitivity to chemothera...

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Autores principales: Berthois, Yolande, Delfino, Christine, Metellus, Philippe, Fina, Frederic, Nanni-Metellus, Isabelle, Al Aswy, Hayat, Pirisi, Victor, Ouafik, L’Houcine, Boudouresque, Françoise
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100995/
https://ncbi.nlm.nih.gov/pubmed/24755707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28920
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