Differential expression of miR200a-3p and miR21 in grade II–III and grade IV gliomas: Evidence that miR200a-3p is regulated by O(6)-methylguanine methyltransferase and promotes temozolomide responsiveness

Glioblastoma multiforme (GBM) is the most common primary brain tumor and is among the deadliest of human cancers. Dysregulation of microRNAs (miRNAs) expression is an important step in tumor progression as miRNAs can act as tumor suppressors or oncogenes and may affect cell sensitivity to chemothera...

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Detalhes bibliográficos
Main Authors: Berthois, Yolande, Delfino, Christine, Metellus, Philippe, Fina, Frederic, Nanni-Metellus, Isabelle, Al Aswy, Hayat, Pirisi, Victor, Ouafik, L’Houcine, Boudouresque, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100995/
https://ncbi.nlm.nih.gov/pubmed/24755707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28920
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