Differential expression of miR200a-3p and miR21 in grade II–III and grade IV gliomas: Evidence that miR200a-3p is regulated by O(6)-methylguanine methyltransferase and promotes temozolomide responsiveness

Glioblastoma multiforme (GBM) is the most common primary brain tumor and is among the deadliest of human cancers. Dysregulation of microRNAs (miRNAs) expression is an important step in tumor progression as miRNAs can act as tumor suppressors or oncogenes and may affect cell sensitivity to chemothera...

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Hlavní autoři: Berthois, Yolande, Delfino, Christine, Metellus, Philippe, Fina, Frederic, Nanni-Metellus, Isabelle, Al Aswy, Hayat, Pirisi, Victor, Ouafik, L’Houcine, Boudouresque, Françoise
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100995/
https://ncbi.nlm.nih.gov/pubmed/24755707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28920
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