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A novel synthetic 1,3-phenyl bis-thiourea compound targets microtubule polymerization to cause cancer cell death
Microtubules are essential cytoskeletal components with a central role in mitosis and have been particularly useful as a cancer chemotherapy target. We synthesized a small molecule derivative of a symmetrical 1,3-phenyl bis-thiourea, (1,1'-[1,3-phenylene]bis[3-(3,5-dimethylphenyl)thiourea], nam...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4100990/ https://ncbi.nlm.nih.gov/pubmed/24755487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28881 |
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