Vemurafenib and panitumumab combination tailored therapy in BRAF-mutated metastatic colorectal cancer: A case report

As the knowledge on cancer genetic alterations progresses, it fosters the need for more personalized therapeutic intervention in modern cancer management. Recently, mutations in KRAS, BRAF, and PIK3CA genes have emerged as important mechanisms of resistance to EGFR-targeted therapy in metastatic col...

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Bibliographic Details
Main Authors: Capalbo, Carlo, Marchetti, Paolo, Coppa, Anna, Calogero, Antonella, Anastasi, Emanuela, Buffone, Amelia, Belardinilli, Francesca, Gulino, Matteo, Frati, Paola, Catalano, Carlo, Cortesi, Enrico, Giannini, Giuseppe, Gulino, Alberto
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
Subjects:
Bedside to Bench Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100983/
https://ncbi.nlm.nih.gov/pubmed/24755613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.28878
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