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Quantitative Determination of Binding of ISWI to Nucleosomes and DNA Shows Allosteric Regulation of DNA Binding by Nucleotides

[Image: see text] The regulation of chromatin structure is controlled by a family of molecular motors called chromatin remodelers. The ability of these enzymes to remodel chromatin structure is dependent on their ability to couple ATP binding and hydrolysis into the mechanical work that drives nucle...

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Autors principals: Al-Ani, Gada, Briggs, Koan, Malik, Shuja Shafi, Conner, Michael, Azuma, Yoshiaki, Fischer, Christopher J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100786/
https://ncbi.nlm.nih.gov/pubmed/24898734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500224t
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