Attenuation of Immune-Mediated Influenza Pneumonia by Targeting the Inducible Co-Stimulator (ICOS) Molecule on T Cells

Inducible Co-stimulator (ICOS) plays a critical role in mediating T cell differentiation and function and is considered a key player in balancing T effector and T regulatory (T(reg)) cell responses. Here we show that activation of the ICOS signalling pathway during acute influenza A virus (IAV) infe...

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Detalhes bibliográficos
Principais autores: Sakthivel, Priya, Gereke, Marcus, Breithaupt, Angele, Fuchs, Dietmar, Gigliotti, Luca, Gruber, Achim D., Dianzani, Umberto, Bruder, Dunja
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100737/
https://ncbi.nlm.nih.gov/pubmed/25029240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100970
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