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SHP2 expression is an independent negative prognostic factor in human breast cancer

AIMS: Src-homology-phosphotyrosyl-phosphatase 2 (SHP2) is a ubiquitously expressed phosphatase that plays an essential role in the downstream signaling pathways of multiple growth factor receptors, thus representing a potential target for cancer therapy. Recent studies suggest that SHP2 contributes...

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Détails bibliographiques
Auteurs principaux: Muenst, S, Obermann, EC, Gao, F, Oertli, D, Viehl, CT, Weber, WP, Fleming, T, Gillanders, WE, Soysal, SD
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100721/
https://ncbi.nlm.nih.gov/pubmed/23672411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/his.12140
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