Identification of specific genes and pathways involved in NSAIDs-induced apoptosis of human colon cancer cells

AIM: To study whether indomethacin (IND), a nonselective cyclooxygenase (COX) inhibitor or NS-398 (NS), a COX-2-selective inhibitor, induces apoptosis in human colon cancer cells and which apoptosis-related genes and pathways are involved. METHODS: Human colon cancer Caco-2 cells were treated with e...

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Autores principales: Huang, Richard H, Chai, Jianyuan, Tarnawski, Andrzej S
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2006
Materias:
Colorectal Cancer
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100633/
https://ncbi.nlm.nih.gov/pubmed/17072976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i40.6446
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