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CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia

Truncation mutations of the receptor cytoplasmic domain for colony-stimulating factor 3 (CSF3R) are frequently seen in severe congenital neutropenia, whereas activating missense mutations affecting the extracellular domain (exon 14) have been described in hereditary neutrophilia and chronic neutroph...

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Autors principals: Pardanani, A, Lasho, TL, Laborde, RR, Elliott, M, Hanson, CA, Knudson, RA, Ketterling, RP, Maxson, JE, Tyner, JW, Tefferi, A
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100617/
https://ncbi.nlm.nih.gov/pubmed/23604229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.122
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