Blockade of TGF- by Catheter-based Local Intravascular Gene Delivery Does Not Alter The In-Stent Neointimal Response, But Enhances Inflammation in Pig Coronary Arteries

BACKGROUND: Extracellular matrix (ECM) accumulation significantly contributes to in-stent restenosis. In this regard, transforming growth factor (TGF)-β, a positive regulator of ECM deposition, may be implicated in in-stent restenosis. The goal of this study was to assess the effect of blockade of T...

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Detalhes bibliográficos
Main Authors: Chung, Ick-Mo, Kim, Junwoo, Pak, Youngmi K, Jang, Yangsoo, Yang, Woo-Ick, Han, Innoc, Park, Seung-Jung, Park, Seong-Wook, Huh, Jooryung, Wight, Thomas N, Ueno, Hikaru
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100469/
https://ncbi.nlm.nih.gov/pubmed/20053468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2009.11.032
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