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Differential Proteomic Analysis of the Pancreas of Diabetic db/db Mice Reveals the Proteins Involved in the Development of Complications of Diabetes Mellitus

Type 2 diabetes mellitus is characterized by hyperglycemia and insulin-resistance. Diabetes results from pancreatic inability to secrete the insulin needed to overcome this resistance. We analyzed the protein profile from the pancreas of ten-week old diabetic db/db and wild type mice through proteom...

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Detalhes bibliográficos
Main Authors: Pérez-Vázquez, Victoriano, Guzmán-Flores, Juan M., Mares-Álvarez, Daniela, Hernández-Ortiz, Magdalena, Macías-Cervantes, Maciste H., Ramírez-Emiliano, Joel, Encarnación-Guevara, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100111/
https://ncbi.nlm.nih.gov/pubmed/24886809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15069579
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