Increase in cell motility by carbon ion irradiation via the Rho signaling pathway and its inhibition by the ROCK inhibitor Y-27632 in lung adenocarcinoma A549 cells

This study aimed to investigate the effect of carbon ion (C-ion) irradiation on cell motility through the ras homolog gene family member (Rho) signaling pathway in the human lung adenocarcinoma cell line A549. Cell motility was assessed by a wound-healing assay, and the formation of cell protrusions...

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Detalhes bibliográficos
Main Authors: Murata, Kazutoshi, Noda, Shin-ei, Oike, Takahiro, Takahashi, Akihisa, Yoshida, Yukari, Suzuki, Yoshiyuki, Ohno, Tatsuya, Funayama, Tomoo, Kobayashi, Yasuhiko, Takahashi, Takeo, Nakano, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099995/
https://ncbi.nlm.nih.gov/pubmed/24659807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rru002
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