Exposure to hycanthone alters chromatin structure around specific gene functions and specific repeats in Schistosoma mansoni

Schistosoma mansoni is a parasitic plathyhelminth responsible for intestinal schistosomiasis (or bilharzia), a disease affecting 67 million people worldwide and causing an important economic burden. The schistosomicides hycanthone, and its later proxy oxamniquine, were widely used for treatments in...

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Detalhes bibliográficos
Main Authors: Roquis, David, Lepesant, Julie M. J., Villafan, Emanuel, Boissier, Jérôme, Vieira, Cristina, Cosseau, Céline, Grunau, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099960/
https://ncbi.nlm.nih.gov/pubmed/25076965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00207
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