Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development

Calcium-dependent protein kinases (PKCs) function in a myriad of cellular processes, including cell-cycle regulation, proliferation, hematopoietic stem cell differentiation, apoptosis, and malignant transformation. PKC inhibitors, when targeted to these pathways, have demonstrated efficacy against s...

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Bibliografski detalji
Glavni autori: Mencalha, André L, Corrêa, Stephany, Abdelhay, Eliana
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2014
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099416/
https://ncbi.nlm.nih.gov/pubmed/25045273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S64303
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