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Lactate and the Lactate-to-Pyruvate Molar Ratio Cannot Be Used as Independent Biomarkers for Monitoring Brain Energetic Metabolism: A Microdialysis Study in Patients with Traumatic Brain Injuries

BACKGROUND: For decades, lactate has been considered an excellent biomarker for oxygen limitation and therefore of organ ischemia. The aim of the present study was to evaluate the frequency of increased brain lactate levels and the LP ratio (LPR) in a cohort of patients with severe or moderate traum...

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Bibliografske podrobnosti
Main Authors: Sahuquillo, Juan, Merino, Maria-Angels, Sánchez-Guerrero, Angela, Arikan, Fuat, Vidal-Jorge, Marian, Martínez-Valverde, Tamara, Rey, Anna, Riveiro, Marilyn, Poca, Maria-Antonia
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099374/
https://ncbi.nlm.nih.gov/pubmed/25025772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102540
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