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Castration of male mice prevents the progression of established angiotensin II-induced abdominal aortic aneurysms
OBJECTIVE: Male sex is a non-modifiable risk factor for abdominal aortic aneurysm (AAA) development. Similar to humans, male mice are more susceptible to angiotensin II (AngII)-induced AAAs than females. Previous studies demonstrated that castration of males markedly reduced the formation of AngII-i...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4099302/ https://ncbi.nlm.nih.gov/pubmed/24439319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2013.11.004 |
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