Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells

Synthetic antagonists of the nuclear receptor PPARγ such as GW9662 are widely used to elucidate receptor-mediated ligand effects. In addition and complementary to recent work, we examined whether GW9662 is suitable to serve for mechanistic investigation in T-helper cells. Human peripheral blood mono...

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Detalhes bibliográficos
Main Authors: Jaudszus, Anke, Lorkowski, Stefan, Gruen, Michael, Roth, Alexander, Jahreis, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099290/
https://ncbi.nlm.nih.gov/pubmed/25054074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/149628
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