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Gene Delivery from Supercharged Coiled-coil Protein and Cationic Lipid Hybrid Complex

A lipoproteoplex comprised of an engineered supercharged coiled-coil protein (CSP) bearing multiple arginines and the cationic lipid formulation FuGENE HD (FG) was developed for effective condensation and delivery of nucleic acids. The CSP was able to maintain helical structure and self-assembly pro...

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Bibliografske podrobnosti
Main Authors: More, Haresh T., Frezzo, Joseph A., Dai, Jisen, Yamano, Seiichi, Montclare, Jin K.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099184/
https://ncbi.nlm.nih.gov/pubmed/24875765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.05.005
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