The Three Receptor Tyrosine Kinases c-KIT, VEGFR2 and PDGFRα, Closely Spaced at 4q12, Show Increased Protein Expression in Triple-Negative Breast Cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is a heterogeneous subgroup of breast cancer with poor prognosis and no targeted therapy available. Receptor tyrosine kinases (RTKs) are emerging targets in anticancer therapy and many RTK-inhibiting drugs are currently being developed. The aim of thi...

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Bibliographic Details
Main Authors: Jansson, Sara, Bendahl, Pär-Ola, Grabau, Dorthe Aamand, Falck, Anna-Karin, Fernö, Mårten, Aaltonen, Kristina, Rydén, Lisa
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098911/
https://ncbi.nlm.nih.gov/pubmed/25025175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102176
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