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Mannosylated Chitosan Nanoparticles for Delivery of Antisense Oligonucleotides for Macrophage Targeting

The therapeutic potential of antisense oligonucleotides (ASODN) is primarily dependent upon its safe and efficient delivery to specific cells overcoming degradation and maximizing cellular uptake in vivo. The present study focuses on designing mannosylated low molecular weight (LMW) chitosan nanocon...

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Autors principals: Shilakari Asthana, Gyati, Asthana, Abhay, Kohli, Dharm Veer, Vyas, Suresh Prasad
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098891/
https://ncbi.nlm.nih.gov/pubmed/25057492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/526391
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