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Mannosylated Chitosan Nanoparticles for Delivery of Antisense Oligonucleotides for Macrophage Targeting

The therapeutic potential of antisense oligonucleotides (ASODN) is primarily dependent upon its safe and efficient delivery to specific cells overcoming degradation and maximizing cellular uptake in vivo. The present study focuses on designing mannosylated low molecular weight (LMW) chitosan nanocon...

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Bibliographic Details
Main Authors: Shilakari Asthana, Gyati, Asthana, Abhay, Kohli, Dharm Veer, Vyas, Suresh Prasad
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098891/
https://ncbi.nlm.nih.gov/pubmed/25057492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/526391
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