Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: A search for biomarkers of sensitivity to treatment

OBJECTIVES: Our goal was to evaluate the effect of rapamycin, an mTOR inhibitor, in type I and II human endometrial cancer tumor explants. METHODS: Short-term tissue culture with fresh endometrial cancer tumor explants was performed. Cell proliferation was assessed by MTS assay after treatment with...

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Hlavní autoři: Bae-Jump, Victoria L., Zhou, Chunxiao, Boggess, John F., Whang, Young E., Barroilhet, Lisa, Gehrig, Paola A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098865/
https://ncbi.nlm.nih.gov/pubmed/20863555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2010.08.025
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