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A monoclonal antibody that targets a Na(V)1.7 channel voltage sensor for pain and itch relief

Voltage-gated sodium (Na(V)) channels control the upstroke of the action potentials in excitable cells. Multiple studies have shown distinct roles of Na(V) channel subtypes in human physiology and diseases, but subtype-specific therapeutics are lacking and the current efforts have been limited to sm...

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Sonraí Bibleagrafaíochta
Main Authors: Lee, Jun-Ho, Park, Chul-Kyu, Chen, Gang, Han, Qingjian, Xie, Rou-Gang, Liu, Tong, Ji, Ru-Rong, Lee, Seok-Yong
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098795/
https://ncbi.nlm.nih.gov/pubmed/24856969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.064
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