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A monoclonal antibody that targets a Na(V)1.7 channel voltage sensor for pain and itch relief
Voltage-gated sodium (Na(V)) channels control the upstroke of the action potentials in excitable cells. Multiple studies have shown distinct roles of Na(V) channel subtypes in human physiology and diseases, but subtype-specific therapeutics are lacking and the current efforts have been limited to sm...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4098795/ https://ncbi.nlm.nih.gov/pubmed/24856969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.064 |
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