Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers

BACKGROUND: The primary objective was to study the antitumor activity of prolonged subcutaneous dosing of systemic 852A, a Toll-like receptor-7 agonist (TLR-7), in recurrent breast, ovarian and cervix cancer. Secondary objectives included assessment of safety and immune system activation. METHODS: A...

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Autori principali: Geller, Melissa A., Cooley, Sarah, Argenta, Peter A., Downs, Levi S., Carson, Linda F., Judson, Patricia L., Ghebre, Rahel, Weigel, Brenda, Panoskaltsis-Mortari, Angela, Curtsinger, Julie, Miller, Jeffrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098785/
https://ncbi.nlm.nih.gov/pubmed/20820775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0914-1
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