Hypothesizing that brain reward circuitry genes are genetic antecedents of pain sensitivity and critical diagnostic and pharmacogenomic treatment targets for chronic pain conditions

While it is well established that the principal ascending pathways for pain originate in the dorsal horn of the spinal cord and in the medulla, the control and sensitivity to pain may reside in additional neurological loci, especially in the mesolimbic system of the brain (i.e., a reward center), an...

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Main Authors: Chen, Amanda L.-C., Chen, Thomas J.H., Waite, Roger L., Reinking, Jeffrey, Tung, Howard L., Rhoades, Patrick, Downs, B. William, Braverman, Eric, Braverman, Dasha, Kerner, Mallory, Blum, Seth H., DiNubile, Nicholas, Smith, David, Oscar-Berman, Marlene, Prihoda, Thomas J., Floyd, John B., O’Brien, David, Liu, H.H., Blum, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098664/
https://ncbi.nlm.nih.gov/pubmed/18951726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2008.07.059
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