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Mechanical strain activates BNP gene transcription through a p38/NF-κB–dependent mechanism

Application of mechanical strain to neonatal rat ventricular myocytes in culture evokes changes in gene expression reminiscent of those that occur with hypertrophy in vivo, such as stimulation of brain natriuretic peptide (BNP) gene expression. Here, we show that a major component of strain-dependen...

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Detalhes bibliográficos
Main Authors: Liang, Faquan, Gardner, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC409860/
https://ncbi.nlm.nih.gov/pubmed/10587524
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