Resistance of young gelatinase B–deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions

Regulated expression of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) plays a role in various physiological processes. To determine in vivo how unbalanced expression of these factors can promote or affect the course of pathologies, we knocked out the mouse gelatinase B gene by replac...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Dubois, Bénédicte, Masure, Stefan, Hurtenbach, Ursula, Paemen, Liesbet, Heremans, Hubertine, van den Oord, Joost, Sciot, Raf, Meinhardt, Thorsten, Hämmerling, Günter, Opdenakker, Ghislain, Arnold, Bernd
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1999
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409857/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10587514/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI6886
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