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Presence of CD8(+) T Cells in the Ectocervical Mucosa Correlates with Genital Viral Shedding in HIV-Infected Women despite a Low Prevalence of HIV RNA–Expressing Cells in the Tissue

The female genital tract is a portal of entry for sexual HIV transmission and a possible viral reservoir. In this study, the ectocervical CD8(+) T cell distribution was explored in situ and was related to expression of CD3 and HLA-DR and presence of HIV RNA. For this purpose, ectocervical tissue sam...

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Bibliografske podrobnosti
Main Authors: Gibbs, Anna, Hirbod, Taha, Li, Qingsheng, Bohman, Karin, Ball, Terry B., Plummer, Francis A., Kaul, Rupert, Kimani, Joshua, Broliden, Kristina, Tjernlund, Annelie
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098133/
https://ncbi.nlm.nih.gov/pubmed/24639358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302826
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