The Mitochondrial Cardiolipin Remodeling Enzyme Lysocardiolipin Acyltransferase Is a Novel Target in Pulmonary Fibrosis

Rationale: Lysocardiolipin acyltransferase (LYCAT), a cardiolipin-remodeling enzyme regulating the 18:2 linoleic acid pattern of mammalian mitochondrial cardiolipin, is necessary for maintaining normal mitochondrial function and vascular development. We hypothesized that modulation of LYCAT expressi...

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Detalhes bibliográficos
Main Authors: Huang, Long Shuang, Mathew, Biji, Li, Haiquan, Zhao, Yutong, Ma, Shwu-Fan, Noth, Imre, Reddy, Sekhar P., Harijith, Anantha, Usatyuk, Peter V., Berdyshev, Evgeny V., Kaminski, Naftali, Zhou, Tong, Zhang, Wei, Zhang, Yanmin, Rehman, Jalees, Kotha, Sainath R., Gurney, Travis O., Parinandi, Narasimham L., Lussier, Yves A., Garcia, Joe G. N., Natarajan, Viswanathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098083/
https://ncbi.nlm.nih.gov/pubmed/24779708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201310-1917OC
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