Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups

Inhaled short-acting beta-agonist (SABA) medication is commonly used in asthma patients to rapidly reverse airway obstruction and improve acute symptoms. We performed a genome wide association study of SABA medication response using gene-based association tests. A linear mixed model approach was fir...

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Hlavní autoři: Padhukasahasram, Badri K., Yang, James J., Levin, Albert M., Yang, Mao, Burchard, Esteban G., Kumar, Rajesh, Kwok, Pui-Yan, Seibold, Max A., Lanfear, David E., Williams, L. Keoki
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098013/
https://ncbi.nlm.nih.gov/pubmed/24418963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2013.49
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