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Evidence That Estrogen Hastens Epiphyseal Fusion and Cessation of Longitudinal Bone Growth by Irreversibly Depleting the Number of Resting Zone Progenitor Cells in Female Rabbits

With age, growth plate cartilage undergoes programmed senescence, eventually causing cessation of bone elongation and epiphyseal fusion. Estrogen accelerates this developmental process. We hypothesized that senescence occurs because progenitor cells in the resting zone are depleted in number and tha...

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Detalhes bibliográficos
Main Authors: Nilsson, Ola, Weise, Martina, Landman, Ellie B.M., Meyers, Jodi L., Barnes, Kevin M., Baron, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098010/
https://ncbi.nlm.nih.gov/pubmed/24708243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2175
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