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Evidence That Estrogen Hastens Epiphyseal Fusion and Cessation of Longitudinal Bone Growth by Irreversibly Depleting the Number of Resting Zone Progenitor Cells in Female Rabbits

With age, growth plate cartilage undergoes programmed senescence, eventually causing cessation of bone elongation and epiphyseal fusion. Estrogen accelerates this developmental process. We hypothesized that senescence occurs because progenitor cells in the resting zone are depleted in number and tha...

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書誌詳細
主要な著者: Nilsson, Ola, Weise, Martina, Landman, Ellie B.M., Meyers, Jodi L., Barnes, Kevin M., Baron, Jeffrey
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098010/
https://ncbi.nlm.nih.gov/pubmed/24708243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2175
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