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Hypothalamic Gliosis Associated With High-Fat Diet Feeding Is Reversible in Mice: A Combined Immunohistochemical and Magnetic Resonance Imaging Study

Gliosis, the activation of astrocyte and microglial cell populations, is a hallmark of central nervous system injury and is detectable using either immunohistochemistry or in vivo magnetic resonance imaging (MRI). Obesity in rodents and humans is associated with gliosis of the arcuate nucleus, a key...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Berkseth, Kathryn E., Guyenet, Stephan J., Melhorn, Susan J., Lee, Donghoon, Thaler, Joshua P., Schur, Ellen A., Schwartz, Michael W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098007/
https://ncbi.nlm.nih.gov/pubmed/24914942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1121
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