Host and Viral Determinants of Mx2 Antiretroviral Activity

Myxovirus resistance 2 (Mx2/MxB) has recently been uncovered as an effector of the anti-HIV-1 activity of type I interferons (IFNs) that inhibits HIV-1 at an early stage postinfection, after reverse transcription but prior to proviral integration into host DNA. The mechanistic details of Mx2 antivir...

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Detalhes bibliográficos
Main Authors: Busnadiego, Idoia, Kane, Melissa, Rihn, Suzannah J., Preugschas, Hannah F., Hughes, Joseph, Blanco-Melo, Daniel, Strouvelle, Victoria P., Zang, Trinity M., Willett, Brian J., Boutell, Chris, Bieniasz, Paul D., Wilson, Sam J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097781/
https://ncbi.nlm.nih.gov/pubmed/24760893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00214-14
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