Extensive Recombination-Induced Disruption of Genetic Interactions Is Highly Deleterious but Can Be Partially Reversed by Small Numbers of Secondary Recombination Events

Although homologous recombination can potentially provide viruses with vastly more evolutionary options than are available through mutation alone, there are considerable limits on the adaptive potential of this important evolutionary process. Primary among these is the disruption of favorable coevol...

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Detalhes bibliográficos
Main Authors: Monjane, Adérito L., Martin, Darren P., Lakay, Francisco, Muhire, Brejnev M., Pande, Daniel, Varsani, Arvind, Harkins, Gordon, Shepherd, Dionne N., Rybicki, Edward P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097777/
https://ncbi.nlm.nih.gov/pubmed/24789787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00709-14
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