Metal-Mediated Modulation of Streptococcal Cysteine Protease Activity and Its Biological Implications

Streptococcal cysteine protease (SpeB), the major secreted protease produced by group A streptococcus (GAS), cleaves both host and bacterial proteins and contributes importantly to the pathogenesis of invasive GAS infections. Modulation of SpeB expression and/or its activity during invasive GAS infe...

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Detalhes bibliográficos
Main Authors: Chella Krishnan, Karthickeyan, Mukundan, Santhosh, Landero Figueroa, Julio A., Caruso, Joseph A., Kotb, Malak
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097633/
https://ncbi.nlm.nih.gov/pubmed/24799625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01770-14
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