Identification of a Diguanylate Cyclase and Its Role in Porphyromonas gingivalis Virulence

Porphyromonas gingivalis is a Gram-negative obligate anaerobic bacterium and is considered a keystone pathogen in the initiation of periodontitis, one of the most widespread infectious diseases. Bacterial bis-(3′-5′) cyclic GMP (cyclic di-GMP [c-di-GMP]) serves as a second messenger and is involved...

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Autori principali: Chaudhuri, Swarnava, Pratap, Siddharth, Paromov, Victor, Li, Zhijun, Mantri, Chinmay K., Xie, Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097614/
https://ncbi.nlm.nih.gov/pubmed/24733094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00084-14
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