VCAM-1/α4β1 Integrin Interaction Is Crucial for Prompt Recruitment of Immune T Cells into the Brain during the Early Stage of Reactivation of Chronic Infection with Toxoplasma gondii To Prevent Toxoplasmic Encephalitis

Reactivation of chronic infection with Toxoplasma gondii can cause life-threatening toxoplasmic encephalitis in immunocompromised individuals. We examined the role of VCAM-1/α4β1 integrin interaction in T cell recruitment to prevent reactivation of the infection in the brain. SCID mice were infected...

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Bibliographic Details
Main Authors: Sa, Qila, Ochiai, Eri, Sengoku, Tomoko, Wilson, Melinda E., Brogli, Morgan, Crutcher, Stephen, Michie, Sara A., Xu, Baohui, Payne, Laura, Wang, Xisheng, Suzuki, Yasuhiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097612/
https://ncbi.nlm.nih.gov/pubmed/24752515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01494-13
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