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Enteropathogenic Escherichia coli Inhibits Type I Interferon- and RNase L-Mediated Host Defense To Disrupt Intestinal Epithelial Cell Barrier Function

Enteropathogenic Escherichia coli (EPEC) primarily infects children in developing countries and causes diarrhea that can be deadly. EPEC pathogenesis occurs through type III secretion system (T3SS)-mediated injection of effectors into intestinal epithelial cells (IECs); these effectors alter actin d...

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Detalhes bibliográficos
Main Authors: Long, Tiha M., Nisa, Shahista, Donnenberg, Michael S., Hassel, Bret A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097611/
https://ncbi.nlm.nih.gov/pubmed/24733098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00105-14
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