Steady-State Hydrogen Peroxide Induces Glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from human pathogens Staphylococcus aureus and Pseudomonas aeruginosa can be readily inhibited by reactive oxygen species (ROS)-mediated direct oxidation of their catalytic active cysteines. Because of the rapid degradation of H(2)O(2) by bacterial ca...

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Autors principals: Deng, Xin, Liang, Haihua, Ulanovskaya, Olesya A., Ji, Quanjiang, Zhou, Tianhong, Sun, Fei, Lu, Zhike, Hutchison, Alan L., Lan, Lefu, Wu, Min, Cravatt, Benjamin F., He, Chuan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097596/
https://ncbi.nlm.nih.gov/pubmed/24769698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01538-14
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