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Streptococcus pyogenes Polymyxin B-Resistant Mutants Display Enhanced ExPortal Integrity

The ExPortal protein secretion organelle in Streptococcus pyogenes is an anionic phospholipid-containing membrane microdomain enriched in Sec translocons and postsecretion protein biogenesis factors. Polymyxin B binds to and disrupts ExPortal integrity, resulting in defective secretion of several to...

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Bibliografiske detaljer
Main Authors: Port, Gary C., Vega, Luis A., Nylander, Andrew B., Caparon, Michael G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097577/
https://ncbi.nlm.nih.gov/pubmed/24794568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01596-14
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