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Exogenous Oct-4 Inhibits Lens Transdifferentiation in the Newt Notophthalmus viridescens

From the cocktail of four factors that were able to induce pluripotent stem cells from differentiated cells, Oct-4, c-Myc, Sox-2 and Klf4, only Oct-4 was not expressed during regeneration in newts. To explore the possible action of this stemness factor we developed an assay where we introduced exoge...

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Detalhes bibliográficos
Main Authors: Bhavsar, Rital B., Tsonis, Panagiotis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097451/
https://ncbi.nlm.nih.gov/pubmed/25019378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102510
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