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Exogenous Oct-4 Inhibits Lens Transdifferentiation in the Newt Notophthalmus viridescens
From the cocktail of four factors that were able to induce pluripotent stem cells from differentiated cells, Oct-4, c-Myc, Sox-2 and Klf4, only Oct-4 was not expressed during regeneration in newts. To explore the possible action of this stemness factor we developed an assay where we introduced exoge...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097451/ https://ncbi.nlm.nih.gov/pubmed/25019378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102510 |
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