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Epitope Mapping of the HSP83.1 Protein of Leishmania braziliensis Discloses Novel Targets for Immunodiagnosis of Tegumentary and Visceral Clinical Forms of Leishmaniasis

Gold standard serological diagnostic methods focus on antigens that elicit a strong humoral immune response that is specific to a certain pathogen. In this study, we used bioinformatics approaches to identify linear B-cell epitopes that are conserved among Leishmania species but are divergent from t...

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Main Authors: Menezes-Souza, Daniel, Mendes, Tiago Antônio de Oliveira, Gomes, Matheus de Souza, Reis-Cunha, João Luís, Nagem, Ronaldo Alves Pinto, Carneiro, Cláudia Martins, Coelho, Eduardo Antônio Ferraz, Galvão, Lúcia Maria da Cunha, Fujiwara, Ricardo Toshio, Bartholomeu, Daniella Castanheira
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097446/
https://ncbi.nlm.nih.gov/pubmed/24807053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00151-14
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