Epitope Mapping of Antibodies to Alpha-Synuclein in LRRK2 Mutation Carriers, Idiopathic Parkinson Disease Patients, and Healthy Controls

Alpha-synuclein (Snca) plays a major role in Parkinson disease (PD). Circulating anti-Snca antibodies has been described in PD patients and healthy controls, but they have been poorly characterized. This study was designed to assess the prevalence of anti-Snca reactivity in human subjects carrying t...

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Autores principales: Alvarez-Castelao, Beatriz, Gorostidi, Ana, Ruíz-Martínez, Javier, López de Munain, Adolfo, Castaño, José G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097207/
https://ncbi.nlm.nih.gov/pubmed/25076905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00169
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