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Critical Role for PAR1 in Kallikrein 6-Mediated Oligodendrogliopathy

Kallikrein 6 (Klk6) is a secreted serine protease preferentially expressed by oligodendroglia in CNS white matter. Elevated levels of Klk6 occur in actively demyelinating multiple sclerosis (MS) lesions and in cases of spinal cord injury (SCI), stroke and glioblastoma. Taken with recent evidence est...

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Detalles Bibliográficos
Main Authors: Burda, Joshua E., Radulovic, Maja, Yoon, Hyesook, Scarisbrick, Isobel A.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097182/
https://ncbi.nlm.nih.gov/pubmed/23832758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22534
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